The current USDA APHIS scrapie eradication program utilizes genotyping for alleles that confer resistance to scrapie.
Genotyping has been utilized in the University of Wyoming Performance Test since 2002. Performance test records from 2002 to 2006 (n=518) were analyzed to determine if any production loss or benefit was associated with scrapie resistance in Rambouillet rams.
Performance of rams with scrapie-resistant genotypes was equal to or better than scrapie-susceptible rams. Based on test performance as an acceptable indicator of sire superiority, selection for rams with scrapie-resistant genotypes should not negatively impact flock performance.
Source: Research in Veterinary Science, October 2008